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Human BodySurprise 4/5Difficulty 3/5Reviewed on September 13, 2026

The interstitium was described as a new human organ in 2018.

Why it is true

The interstitium is a network of fluid-filled spaces beneath the skin and surrounding muscles and organs. It may contain about 10 litres of lymph and acts as a shock absorber. The discovery was published in the journal Scientific Reports.

Source: NIH

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